For decades, scientists believed a fertilized egg’s DNA began as a shapeless mass, only organizing itself once the embryo switched on its genes. But new research reveals that the genome is already ...

For decades, scientists viewed the genome of a newly fertilised egg as a structural 'blank slate' – a disordered tangle of ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

For many years, researchers believed that the DNA inside a newly fertilized egg began as a structural ‘blank slate’ – a loose ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Until now, scientists had believed that ...

On February 28, 1953, two scientists, James Watson and Francis Crick, announced they had figured out the structure of DNA.

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...