In the ongoing search for better fluorinating reagents, solid reagents and new coupling reactions are showing promise. Fluorine atoms have a unique combination of electronic and physical properties.
In this report we disclose new SnAP reagents for the synthesis of saturated N-heterocycles with seven-, eight- and nine-membered rings, including oxazepanes, tetrahydrobenzoxazepines, diazepanes, ...
The substrate cocktail is frequently used to evaluate cytochrome P450 (CYP) enzyme-mediated drug interactions and potential interactions among the probe substrates. Here, we re-optimized the substrate ...
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