Everyday Health

What to Expect When Starting CAR T-Cell Therapy for Large B-Cell Lymphoma

I f your doctor has recommended chimeric antigen receptor (CAR) T-cell immunotherapy for large B-cell lymphoma (LBCL), you’ve likely already tried several standard treatments, and the cancer did not ...
University of California, San Francisco

The Liver’s Immune Cells Might Be the Key to Curing Hepatitis B

Jody Baron and Gabi Fragiadakis discover why some people with chronic Hepatitis B are cured after they're taken off of ...
C&EN

mRNA-based therapy creates CAR-T immune cells within the body

The latest chemistry news, including important research advances, business and policy trends, chemical safety practices, career guidance, and more. Current approved CAR T-cell therapy treatments rely ...
Medical Xpress

B-cell lymphoma study identifies traits tied to greatest benefit from CD19 CAR T cell therapy

In the largest study of its kind, researchers from The University of Texas MD Anderson Cancer Center identified three subgroups of patients with large B-cell lymphoma (LBCL) who have different levels ...
The Scientist

CRISPR-Engineered B Cells Dampen Autoimmune Responses in Mice

Gene-edited regulatory B cells could suppress overactive immune responses, potentially helping in the treatment of autoimmune ...

Immunologist's lab demonstrates the power of B cells to gather and defend organs against cancer

Creativity and curiosity have always been central to the work of Joshua Moreau, Ph.D., an immunologist whose work at Oregon ...
Phys.org

Lipid nanoparticles that engineer CAR T cells in vivo could unlock access for millions of autoimmune patients

Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without laboratory cell manufacturing and ex vivo expansion. The method using targeted ...