Mission Bio De-risks CRISPR-Engineered T Cells Through Single-Cell Analysis of Genomic Edits and Gene Expression

Mission Bio, the single-cell multi-omics leader, today released data showing that its Targeted Single-Cell DNA+RNA Assay ...
BioSpace

4 spaces primed for the next wave of gene therapies

The recent approval of Regeneron’s Otarmeni underscores the maturation of gene therapies across a range of diseases. Here, ...
Nature

Target enrichment smooths the path to safe gene therapies

As a fast and easy-to-use gene-editing technique, CRISPR is one of the biggest discoveries in 21 st century medical science, and an important facilitator of gene therapy development. Several gene ...
EurekAlert!

Pusan National University researchers developed an advanced AI model for accelerating therapeutic gene target discovery

Traditional methods for identifying therapeutic gene targets, crucial for personalized medicine, are expensive and time-consuming. While artificial intelligence (AI), particularly deep learning ...
The Scientist

What Is RNAi? Gene Silencing Explained for Researchers and Innovators

The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi pathway. When miRNA acts as the guide for RNAi, only a ...
Singularity Hub

Scientists Target Incurable Mitochondrial Diseases With New Gene Editing Tools

The energy factories in our cells contain their own genes, and genetic mutations in them can cause deadly inherited diseases. These oblong-shaped organelles, or mitochondria, translate genes into ...