The EndRAD study showed non-TBI conditioning in B-ALL patients achieved comparable EFS and OS rates to TBI-based regimens. The trial's primary endpoint was met with a two-year EFS rate of 76.3% and an ...

Cigarette Smoking Prior to First Cancer and Risk of Second Smoking-Associated Cancers Among Survivors of Bladder, Kidney, Head and Neck, and Stage I Lung Cancers Pediatric patients who were scheduled ...

CNS relapse occurred in 5.1% of adults with acute lymphoblastic leukaemia after transplant, with higher risk linked to Philadelphia chromosome positive disease.

ORLANDO -- A conditioning regimen free from total body irradiation (TBI) appeared to be just as effective as standard of care (SoC) in a common type of childhood leukemia, according to a phase II ...

In a new trial, patients with B-acute lymphoblastic leukemia (B-ALL) who had no evidence of remaining cancer cells after prior treatment, experienced comparable outcomes whether they received ...

Bone marrow transplantation (BMT) is being used increasingly for the treatment of pediatric malignancies and aplastic anemia. Conditioning regimens used prior to BMT may cause neurotoxicity, ...

Mesenchymal stromal cells for the prophylaxis of graft-versus-host disease after hematopoietic stem cell transplantation: A meta-analysis of randomized controlled trials. This is an ASCO Meeting ...

The study evaluated a reduced-intensity conditioning regimen without total body irradiation for alloHCT in DC/TBD patients. Non-TBI patients showed similar graft failure, GVHD, and overall survival ...