Transcription initiation and elongation of HIV-1 are critical processes regulating viral latency and activation. Despite these two processes playing essential roles in HIV-1 gene expression, how they ...

To support drug discovery, a new study has revealed fundamental features of the transcription cycle in the bacteria that causes tuberculosis.

This is a preview. Log in through your library . Abstract RNA polymerase II (Pol II) generally pauses at certain positions along gene bodies, thereby interrupting the transcription elongation process, ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...

According to this model, sigma (σ) factors bind to RNA polymerase to initiate transcription—the process by which genetic information is copied from DNA to RNA—and then detach after initiation to allow ...

A new study overturns a central textbook model of bacterial gene regulation and unveils new paths for understanding bacterial gene regulation and its evolution. This could help designing better ...

Indian scientists have helped overturn a 50-year-old model explaining how bacteria regulate their genes, challenging a foundational concept in molecular biology.