Initiation of DNA synthesis: a general model from studies with prokaryotes -- Escherichia coli oriC -- Lambda phage origin: a familiar refrain -- Regulatory transcription factors and the initiation of ...

Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell ...

When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

Molecular biologists have long believed that the beginning of a gene launched the process of transcription—the process by ...

Aging, neurological diseases and our bodies' stress response are all linked to the tiny power plants inside each cell known as mitochondria. To function properly, mitochondria must first read ...

Transcription factors are the most powerful genes in our body. They are master regulators and have been implicated in our biggest diseases, even aging itself. Yet, many in the pharmaceutical industry ...

Intrinsically disordered regions in transcription factors enhance both target binding probability and search efficiency.

Dr. Graham Erwin, assistant professor of molecular and human genetics at Baylor College of Medicine, has been awarded the National Institutes of ...