Reducing the levels of triglycerides and triglyceride-rich lipoproteins remains an unmet clinical need. Olezarsen is an antisense oligonucleotide targeting messenger RNA for apolipoprotein C-III ...

High triglyceride levels are associated with increased cardiovascular risk, but whether reductions in these levels would lower the incidence of cardiovascular events is uncertain. Pemafibrate, a ...

Fat molecules serve as energy storage for fat cells. They consist of three fatty acids attached to a backbone of glycerol. They are therefore also called triglycerides. It has long been suspected that ...

High levels of triglycerides, the most common type of fat in the body and the foods we eat, directly cause abdominal aortic aneurysms, according to a study in mouse models led by Michigan Medicine.

Persistent chylomicronemia is usually caused by familial chylomicronemia syndrome, but it can have multifactorial causes. People with persistent chylomicronemia have impaired clearance of chylomicrons ...

Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) on Tuesday released topline results from the pivotal Phase 3 CORE and CORE2 studies of olezarsen for severe hypertriglyceridemia (sHTG). sHTG is a condition ...

Know how excess sugar quietly harms your cholesterol, raises triglycerides, and impacts heart health. Learn tips to reduce ...