With laboratory methods and diagnostics advancing apace, Francesca Lake considers whether PCR is likely to retain its crown as an essential lab method, or whether it could be replaced and consigned to ...

Note: An expanded version of this article, with complete Methods and Materials, is available exclusively in Web Extras. Quantitative reverse transcriptase (RT) PCR has evolved into a widely used tool ...

In vitro diagnostics (IVD) is an umbrella term for tests conducted on blood or tissue samples to detect diseases, determine the efficacy of novel or established treatments, and monitor health.

Since its invention in the 1980s, polymerase chain reaction (PCR) opened the door for applications such as genetic engineering, genotyping, and sequencing, and has become a fundamental part of ...

This release is available in Spanish. A new procedure devised by U.S. Department of Agriculture (USDA) scientists and colleagues can improve polymerase chain reaction (PCR)-based methods of detecting ...

Digital PCR (dPCR) is the third generation of PCR technology, after conventional PCR and real-time quantitative PCR. It offers significant benefits over these other methods, making it ideal for a wide ...

Objective: To evaluate the detection performance of microfluidic chip-based multiplex PCR technology for rapid detection of ...

In its formative years PCR and its intellectual possessors had to go through some legal wrangling over the originality of the technique. In point of fact, a 13-year earlier paper by Nobelist Gobind ...

There are two main ways to test for infection with SARS-CoV2 (the coronavirus that causes COVID-19 disease). The first is a very sensitive test that looks for the RNA of the virus using a technique ...