V(D)J recombination is a fundamental genetic mechanism that underpins the adaptive immune response in jawed vertebrates. This process orchestrates the rearrangement of variable (V), diversity (D) and ...
DNA segments that are naturally excised during immune-cell development can replicate, drive damage at various genomic sites and lead to cancer recurrence. Karla K. Rodgers is in the Department of ...
One of the remaining mysteries of immunology is the exact mechanism that B cells use to generate millions of antibodies with different specificities to protect us from the plethora of pathogens in the ...
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