New antiviral drugs in development could offer the strongest line of defense yet against COVID-19 and other coronaviruses, ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research reveals new aspects of BKPyV replication, offering possible drug targets ...

Viruses use the molecular repertoire of the host cell to replicate. Researchers want to exploit this for the treatment of influenza. The team identified a compound that inhibits the body's own ...

This story is part of a larger series on viroids and virusoids, small infectious RNAs. It is also the fifth installment in a series on hepatitis D virus, a virusoid-like pathogen that causes serious ...

The replication of potentially harmful adenoviruses can be significantly reduced in human cells in cell culture by using the so-called CRISPR-Cas9 system ("gene scissors"). This method, which is used ...

As the world recovers from the economic and social impacts of COVID-19, researchers like Mattia Bacca continue to study SARS-CoV-2 and related viruses to be better prepared for future pandemics. Dr.

Human norovirus, a positive-strand RNA virus that is the leading cause of viral gastroenteritis accounting for an estimated 685 million cases and approximately 212,000 deaths globally per year, has no ...

Matthew Taylor likened his recently published work alongside doctoral student Gary Dunn to kicking over a rock. Once the ...

Researchers at Johns Hopkins Medicine, in collaboration with researchers at the National Institutes of Health, report that two new studies in mice with a humanized immune system and human cell lines ...

A new antiretroviral target has been identified that suppresses HIV-1 replication and selectively kills HIV-1-infected cells. HIV-1 is the most common type of HIV. When HIV-1 leaves infected cells, ...