An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles. Actin filaments -- protein structures critical to living movement ...
Actin filaments are protein fibers that make up the internal skeleton of the cell. As active elements of our cells, actin filaments support the cell's fusion, movement and are involved in many other ...
Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing ...
The three-dimensional structure of a protein involved in the assembly of actin filaments could help to settle a long-standing scientific debate about the regulation of cytoskeletal organization. The ...
Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through ...
Actin filaments are part of the cell skeleton and essential for stability and motility. They form a network that dynamically builds up and gets broken down by the addition or detachment of building ...
Formins are made of two identical parts (red, orange) that encircle the actin (grey) filament in a ring-like conformation. “Our discovery allows us to interpret decades of biochemical studies on ...
For immune cells, the actin cytoskeleton is more than a structural scaffold. Immune cells can migrate to sites of infection or form precise, short-lived contacts with other cells, by constantly ...
Arp2/3 complex nucleates branched actin filaments important for cellular motility and endocytosis. WASP family proteins are Arp2/3 complex activators that play multiple roles in branching nucleation, ...
Metastases occur when cancer cells leave a primary tumor and spread throughout the body. For this, they have to break connections with neighboring cells and migrate to other tissues. Both processes ...
11don MSN
Huntingtin protein arranges cytoskeletal filaments, offering insight into neurodegeneration
Huntington's disease is a rare genetic disorder and a representative neurodegenerative disease, characterized by loss of ...
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