Objectives The oral microbiome plays a critical role in modulating systemic inflammation, partly through its interactions ...

Objective Idiopathic inflammatory myopathies (IIM) are a heterogenous group of conditions with substantial morbidity but ...

Objective The primary objective was to assess sex differences in long-term functional deterioration and permanent work ...

Objectives Medication adherence is a key determinant of treatment effectiveness in chronic inflammatory diseases but data in ...

Objective To evaluate the diagnostic pathway of patients affected by large vessel vasculitis (LVV) and to determine factors ...

Systemic sclerosis (SSc) is a rare, heterogeneous, systemic autoimmune rheumatic disease characterised by vasculopathy, ...

Introduction Despite better therapies and strategies, many people with rheumatoid arthritis (RA) have persistent pain, often from abnormal pain processing, now termed nociplastic pain. However, RA ...

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RMD Open publishes high quality peer-reviewed original research covering the full spectrum of musculoskeletal disorders, rheumatism and connective tissue diseases, including osteoporosis, spine and ...

The VEXAS syndrome (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) is an adult-onset systemic autoinflammatory condition that is caused by an acquired deficiency of the UBA1 gene in ...

Objective Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is characterised by progressive pulmonary fibrosis. This study aimed to investigate the role of programmed death-1 ...

Objective A new adult-onset autoinflammatory syndrome has been described, named VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic). We aimed to compare the clinical characteristics, the ...