Serious fungal infections are on the rise, and many hospital-acquired cases are becoming harder to treat as fungi become ...

The heightened intrinsic activity resulting from loop confinement in enzymes arises synergistically from enthalpic and entropic contributions, which are contingent upon the extent of surface ...

Researchers from Drexel University’s College of Arts and Sciences and College of Medicine have found a potential new therapeutic target for Alzheimer’s disease. Expanding on their previous research on ...

New analytical methods developed at Baylor College of Medicine and collaborating institutions have increased our ...

Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme’s ligand-binding site, interfering with recognition and binding to the glycosylation proteins’ normal glycoprotein ...

Enzyme assays are essential tools for understanding how enzymes function, from drug discovery to food science. Careful control of assay conditions, awareness of kinetic complexities, and adoption of ...

Life has evolved over billions of years, adapting to the changing environment. Similarly, enzymes—proteins that speed up biochemical reactions (catalysis) in cells—have adapted to the habitats of ...

Imagine trying to bake a cake without heat. You’ve got all the ingredients like flour, eggs and sugar, but nothing is happening. That’s what your body would be like without enzymes: potential but no ...

A platform to engineer enzymes responsible for the formation of amide bonds as an effort toward developing biocatalysts for green chemistry. Amide bonds — a type of chemical bond formed between a ...

A precision cancer strategy that selectively kills tumour cells while leaving healthy tissue intact may be within reach for the majority of colorectal cancer patients, according to new research ...