Phase I study of ixabepilone in combination with capecitabine in Japanese patients with metastatic breast cancer previously treated with an anthracycline and a taxane. Background: Trabectedin (Tr) is ...

The customary approach to early-phase clinical trial design, where the focus is on identification of the maximum tolerated dose, is not always suitable for noncytotoxic or other targeted therapies.

Energy (or, more specifically, energy consumption) is at the forefront in everyone's mind these days. Whether we are sensitive to the cost of fuel, to the electricity bill or to a dead cell phone ...