High-intensity focused ultrasound (HIFU) is an increasingly used, locally ablative therapy option in localized prostate cancer (PCa). Multiparametric MRI (mpMRI) is currently used for tumor ...
Nuclear medicine has undergone a remarkable transformation, with both diagnostic and therapeutic applications expanding at an unprecedented pace. This progress is rooted in fundamental discoveries by ...
See an invited perspective on this article on page 1412. Tumor growth and spread are determined not only by cancer cells but also by the nonmalignant constituents of the malignant lesion, which are ...
The deployment of artificial intelligence (AI) has the potential to make nuclear medicine and medical imaging faster, cheaper, and both more effective and more accessible. This is possible, however, ...
The field of theranostics dates back over 80 y, when Hertz and Roberts first used radioactive iodine to treat thyroid disease. Recent theranostic approvals for neuroendocrine tumors and prostate ...
Amyloid-β (Aβ) accumulation in the brain is a pathologic indicator of Alzheimer disease (AD) that can be imaged using PET. Second-generation PET radiotracers, such as [18 F]florbetaben, [18 ...
Journal of Nuclear Medicine November 2025, jnumed.125.270568; DOI: https://doi.org/10.2967/jnumed.125.270568 ...
Journal of Nuclear Medicine December 2025, jnumed.125.270802; DOI: https://doi.org/10.2967/jnumed.125.270802 ...
The aim of this study was to prospectively compare whole-body PET/MR imaging and PET/CT, qualitatively and quantitatively, in oncologic patients and assess the confidence and degree of inter- and ...
Reactive oxygen species (ROS) play a pivotal role in many cellular processes and can be either beneficial or harmful. The design of ROS-sensitive fluorophores has allowed for imaging of specific ...
Most well-differentiated neuroendocrine tumors (NETs) express high levels of somatostatin receptors, particularly subtypes 2 and 5. Somatostatin analogs (SSAs) bind to somatostatin receptors and are ...
Journal of Nuclear Medicine November 2025, jnumed.125.270481; DOI: https://doi.org/10.2967/jnumed.125.270481 ...
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