Objective Systemic lupus erythematosus (SLE) is associated with increased susceptibility to infections, including herpes ...

Nailfold capillaroscopy is a non-invasive imaging technique for morphological assessment of capillaries in the nailfold area and represents a key method for differentiation of primary and secondary ...

Objective Treatment response in lupus nephritis (LN) is defined based on proteinuria, yet protocol kidney biopsy studies have shown that patients with lupus can have active nephritis in the absence of ...

Objective Simple measures of type I interferon (IFN) activity constitute highly attractive biomarkers in systemic lupus erythematosus (SLE). We explore galectin-3-binding protein (G3BP) as a novel ...

Objectives To report a case of secondary hemophagocytic lymphohistiocytosis (HLH) in a patient with systemic lupus erythematosus (SLE), highlighting its challenges and successful treatment with IL-1 ...

Objective No studies have investigated the incidence and correlation of scarring and dyspigmentation across all cutaneous lupus erythematosus (CLE) categories and subtypes. As better characterisation ...

Objectives The management of SLE varies worldwide. Current SLE treatment goals focus on controlling disease activity and preventing flares and organ damage accrual. LupusNet is the largest federated ...

Objectives Patients with systemic lupus erythematosus (SLE) face a dramatically increased risk of cardiovascular and thromboembolic events yet predicting who will develop these complications remains ...

Objectives Primary antiphospholipid syndrome (pAPS) is an autoimmune disease that, unlike other autoimmune diseases, commonly presents with thrombotic events rather than inflammatory manifestations. A ...

Objectives To assess the prevalence of major bleeding (MB) at delivery in pregnant women with systemic lupus erythematosus (SLE) and to characterize MB cases, focusing on the use of antithrombotic ...

Objectives Trimethylamine N-oxide (TMAO), a gut microbiota–derived metabolite, is associated with cardiovascular disease (CVD) via pro-inflammatory and pro-atherogenic mechanisms. Systemic lupus ...

Objectives To assess hemostatic parameters in SLE patients in relation to disease activity, kidney involvement and presence of extraglomerular vascular changes in kidney biopsies. Methods This ...