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A protein that stops cells from dividing in response to damage or stress could be a new biomarker or therapeutic target for metabolic dysfunction-associated steatotic liver disease (MASLD ...
The findings suggest that decreased protein mobility—the team call this mobility defect proteolethargy—may play a key role in decreased cellular function in chronic disease.
This study introduces a novel method for delivering therapeutic proteins intracellularly using engineered extracellular vesicles (EVs). This method, called IDEA (intracellular delivery via EV ...
One of the challenges of enhancing the therapeutic capabilities of this beneficial microbe was to enable it to secrete proteins into its surroundings. E. coli are surrounded by an outer envelope ...
Discovery of a protein showed signs of being a possible therapeutic target for monoclonal antibody treatment in sepsis and for other infectious diseases, including COVID-19.
The researchers now would use the same lipid nanoparticle delivery concept – the same materials even – but with a protein payload. The trick would be to make proteins look more like nucleic acids.