Aidan O’Brien’s Betfred 2000 Guineas hope Twain has been declared a major doubt for Saturday’s opening Classic of the season at Newmarket.

The drug maker said it is ‘firmly committed to investing and growing in the US’ amid potential import tariffs on the pharmaceutical industry.

The opening of a new Government centre near York marks a step change in the way the country will prepare for future crises and emergencies, ...

Play at the Madrid Open will resume as scheduled on Tuesday following Monday’s power cut. The outage, which affected much of Spain and Portugal, forced play to be suspended just after 12.30pm local ...