Aggregation can occur across the process of making a therapeutic protein. Upstream, cell growth and protein stability depend on many factors and conditions, including aeration, agitation, antifoam ...

Staying within the therapeutic window is important as too much of the protein could be toxic, and too little could result in a small or no therapeutic effect. Although the principle of therapeutic ...

In this study, researchers combined Insilico's proprietary artificial intelligence (AI)-driven target identification engine PandaOmics with the FuzDrop method for predicting protein separation to ...

NJIT researchers unlock a new method for testing protein-based drugs Researchers say a newly developed lab technique could spark a 'paradigm shift' in biopharmaceuticals testing, promising to ...

This study introduces a novel method for delivering therapeutic proteins intracellularly using engineered extracellular vesicles (EVs). This method, called IDEA (intracellular delivery via EV ...

Future Outlook Future research should identify novel proteins and metabolites synthesized by plants and further explore using plant-based molecular farming to produce therapeutic proteins. “It's in ...

The findings suggest that decreased protein mobility—the team call this mobility defect proteolethargy—may play a key role in decreased cellular function in chronic disease.

They also engineered a variety of proteins of therapeutic value to be recognized as secreted proteins of this machine. The resulting programmable platform is referred to as PROT 3 EcT for ...

An Antibacterial protein, a new therapeutic target against pancreatic cancer A research team from Spanish National Research Council describes how tumor stem cells take advantage of the PGLYRP1 ...