The NFC West is the NFL's best division going into Week 16 of the 2025 NFL season. The Rams (11-3), Seahawks (11-3) and 49ers (10-4) all would be in the playoffs and those records suggest anything can happen in the division race over the final three weeks.

The San Francisco 49ers won't play their Week 16 game until Monday night, but they've already benefitted from a massive game on Thursday night.

The San Francisco 49ers are back in playoff contention in 2025. Here's a look at the latest odds, updated NFC playoff picture and remaining schedule.

The NFC West is the NFL's best division going into Week 16 of the 2025 NFL season. The Rams (11-3), Seahawks (11-3) and 49ers (10-4) all would be in the playoffs and those records suggest anything can happen in the division race over the final three weeks.

The Rams can clinch a playoff spot vs. the Lions, but 49ers analysts and fans are openly rooting for Detroit to win and keep the NFC West race alive.

Brandon Aiyuk has not played this season after suffering a torn ACL and MCL in Week 7 of the 2024 campaign, and San Francisco 49ers head coach Kyle Shanahan said Thursday he hasn't heard much from the wide receiver since the setback.

The San Francisco 49ers sit at 9-4 and the No. 6 seed in the NFC after their long-awaited bye week. With the 2-11 Tennessee Titans coming into San Francisco on Sunday, it is safe to say the 49ers have a very realistic chance to reach 10-4 by the end of the week — a remarkable outcome considering the injuries that have plagued this team.

The Seattle Seahawks rallied to beat the Los Angeles Rams 38-37 in overtime to take over first place in the NFC West. In overtime, Sam Darnold hit Jaxon Smith-Njigba for a 4-yard touchdown pass — then connected with Eric Saubert for a 2-point conversion and the win.